Unlock the Mysteries of Chronic Rejection in Organ Transplantation
Despite advancements in antirejection therapies, solid organ transplantation remains challenged by chronic rejection. Alarmingly, approximately 70% of transplants face rejection within a decade post-procedure. As the demand for organ transplants grows and donor availability diminishes, finding a cure for chronic rejection becomes ever more critical. While research into chronic rejection has expanded our understanding, the cellular and molecular processes involved are still not fully comprehended.
This volume offers a deep dive into the molecular and cellular aspects of chronic rejection affecting both solid and composite allografts. It is thoughtfully divided into three insightful parts:
- Part I: Provides a comprehensive overview and a mechanistic understanding of the cellular and molecular pathways that underpin chronic rejection. Discover their potential in identifying novel biomarkers and developing targeted anti-chronic rejection strategies.
- Part II: Focuses on the roles of immune cells, non-immune cells, and extracellular molecules within the context of chronic rejection.
- Part III: Concentrates on shared and organ-specific features, including liver, face, kidney, and lung transplants, alongside the latest therapeutic approaches in combating chronic rejection.
This book offers a thorough exploration of the mechanisms and challenges faced in chronic rejection, aiming to inspire the development of innovative therapies. Ideal for researchers, medical professionals, and students in the fields of transplantation and immunology, this volume stands as a beacon of knowledge and hope for future advancements.
Experience a compelling journey into the intricacies of chronic rejection and enhance your understanding of this crucial area of <em
Authors:
Malgorzata Kloc (Editor)
Publication Date:
January 1, 2026
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