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Jasper’s Basic Mechanisms of the Epilepsies has been the definitive reference in the field of basic research on epilepsies for over five decades, spanning four esteemed editions. Since its inception, this essential volume has been a must-read for every experimental epilepsy investigator, practicing epileptologist, clinical neuroscientist, and student, serving as a vital resource for both clinical and basic science reference, as well as for doctoral and board exam preparation.
This fifth edition is the most ambitious yet, continuing its legacy as the authoritative reference in the field. It offers encyclopedic and updated coverage of the current understanding of basic research in the epilepsies, while also paving the way for new research directions over the next decade. Notably, it reviews how molecular laboratory evidence is being translated into innovative therapeutics.
In its 79 comprehensive chapters, this edition delves into the intricate roles of interactions among neurons, synapses, and glia in the initiation, spread, and arrest of seizures. It meticulously examines mechanisms of excitability, synchronization, and seizure susceptibility, ultimately elucidating their contributions to epileptogenesis. Furthermore, it provides a framework for expanding the monogenic epilepsy genome and understanding the complex heredity responsible for common epilepsies.
Additionally, the book explores the molecular and cellular
Authors:
Jeffrey L. Noebels (Editor),
Edition:
5th
Publication Date:
May 7, 2024
