This comprehensive book, “Renin-Angiotensin System in Cardiovascular Disease”, is an authoritative resource featuring 25 in-depth chapters, carefully organized into three essential sections: modulatory aspects, pathophysiological aspects, and pharmacotherapeutic aspects. Delve into the latest scientific insights and extensive knowledge on the molecular and cellular dynamics of the renin-angiotensin system (RAS) and its pivotal role in the pathophysiology and treatment of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure.
Emphasizing the critical molecular and cellular mechanisms and the signaling transduction pathways, this book explores how prolonged RAS activation contributes to various cardiovascular diseases. It also outlines the biochemical strategies for inhibiting this system, focusing on the blockade of angiotensin-converting enzyme and angiotensin II type 1 receptors in patients with cardiovascular conditions. Given that cardiovascular disease is the leading cause of death globally, accounting for approximately 17.9 million deaths annually, understanding its pathogenesis and improving therapy is of paramount importance.
Authored by a selection of renowned global experts, this book covers diverse aspects of cardiovascular science and the molecular mechanisms of angiotensin II action in the development of cardiovascular abnormalities. Perfect for health professionals involved in both experimental and clinical cardiology, as well as academic investigators, cardiovascular scientists, graduate students, and fellows worldwide, this book is an invaluable resource for those seeking to deepen their understanding of RAS biology.
Discover more about the essential components of RAS and their role in cardiovascular disease development.
Authors:
Naranjan S. Dhalla (Editor)
Edition:
Publication Date:
January 1, 2023
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